Friday, May 31, 2019

World Pharmacology



Pharmacology is the main branch of biology concerned with the study of Drug or Medication action, where a drug can be broadly Specify as any man-made, natural, or endogenous molecule which exerts a biochemical or physiological effect on the cell and tissue, organ, or organism (sometimes the word pharma on is used as a term to encompass these endogenous and exogenous bioactive species). More specifically, it is the study of the communication that occurs between a living organism and chemicals that affect abnormal or normal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals.



The field encompasses drug composition and properties, synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, toxicology, chemical biology, therapy, and medical applications and antpathogenic capabilities. The two main areas of pharmacology are pharmacodynamics and pharmacokinetics. Pharmacodynamics studies the effects of a drug on biological systems, and Pharmacokinetics studies the effects of biological systems on a drug. In broad terms, pharmacodynamics discusses the chemicals with biological receptors, and pharmacokinetics discusses the absorption, distribution, metabolism, and excretion (ADME) of chemicals from the biological systems. Pharmacology is not synonymous with pharmacy and the two terms are frequently confused. Pharmacology, a biomedical science, deals with the research, discovery, and characterization of chemicals which show biological effects and the elucidation of cellular and organism function in relation to these chemicals. In contrast, pharmacy, a health services profession, is concerned with application of the principles learned from pharmacology in its clinical settings; whether it is in a dispensing or clinical care role. In either field, the primary contrast between the two are their distinctions between direct-patient cares, for pharmacy practice, and the science-oriented research field, driven by pharmacology.




Pharmacological knowledge is used to advise chemotherapy in medicine and pharmacy. The International Union of Basic and Clinical Pharmacology, Federation of European Pharmacological Societies and European Association for Clinical Pharmacology and Therapeutics are organisations representing standardization and regulation of clinical and scientific pharmacology. Systems for medical classification of drugs with pharmaceutical codes have been developed. These include the National Drug Code (NDC), administered by Food and Drug Administration; Drug Identification Number (DIN), administered by Health Canada under the Food and Drugs Act; Hong Kong Drug Registration, administered by the Pharmaceutical Service of the Department of Health (Hong Kong) and National Pharmaceutical Product Index in South Africa. Hierarchical systems have also been developed, including the Anatomical Therapeutic Chemical Classification System (AT, or ATC/DDD), administered by World Health Organization; Generic Product Identifier (GPI).

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