Pharmacology is the main branch of biology concerned with the study of Drug or Medication action,
where a drug can be broadly Specify as any man-made, natural, or endogenous
molecule which exerts a biochemical or physiological effect on the cell and
tissue, organ, or organism (sometimes the word pharma on is used as a term to
encompass these endogenous and exogenous bioactive species). More specifically,
it is the study of the communication that occurs between a living organism and
chemicals that affect abnormal or normal biochemical function. If substances
have medicinal properties, they are considered pharmaceuticals.
The field encompasses drug composition and properties, synthesis and
drug design, molecular and cellular mechanisms, organ/systems mechanisms,
signal transduction/cellular communication, molecular diagnostics,
interactions, toxicology, chemical biology, therapy, and medical applications
and antpathogenic capabilities. The two main areas of pharmacology are
pharmacodynamics and pharmacokinetics. Pharmacodynamics
studies the effects of a drug on biological systems, and Pharmacokinetics
studies the effects of biological systems on a drug. In broad terms, pharmacodynamics
discusses the chemicals with biological receptors, and pharmacokinetics
discusses the absorption, distribution, metabolism, and excretion (ADME) of
chemicals from the biological systems. Pharmacology is not synonymous with
pharmacy and the two terms are frequently confused. Pharmacology, a biomedical
science, deals with the research, discovery, and characterization of chemicals
which show biological effects and the elucidation of cellular and organism
function in relation to these chemicals. In contrast, pharmacy, a health
services profession, is concerned with application of the principles learned
from pharmacology in its clinical settings; whether it is in a dispensing or
clinical care role. In either field, the primary contrast between the two are
their distinctions between direct-patient cares, for pharmacy practice, and the
science-oriented research field, driven by pharmacology.
Pharmacological knowledge is used
to advise chemotherapy in medicine and pharmacy. The International Union of
Basic and Clinical Pharmacology, Federation of European Pharmacological
Societies and European Association for Clinical Pharmacology and Therapeutics
are organisations representing standardization and regulation of clinical and
scientific pharmacology. Systems for medical classification of drugs with
pharmaceutical codes have been developed. These include the National Drug Code
(NDC), administered by Food
and Drug Administration; Drug Identification Number (DIN), administered by
Health Canada under the Food and Drugs Act; Hong Kong Drug Registration,
administered by the Pharmaceutical Service of the Department of Health (Hong
Kong) and National Pharmaceutical Product Index in South Africa. Hierarchical
systems have also been developed, including the Anatomical Therapeutic Chemical
Classification System (AT, or ATC/DDD), administered by World Health
Organization; Generic Product Identifier (GPI).
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